Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003497 | 0.82 | KMT2A (0.51) | ARKMT2APIK3CDPIK3CAPIK3CB | |
| SCHEMBL28003521 | 0.80 | AR (0.56) | ARKMT2APIK3CDPIK3CAPIK3CB | |
| SCHEMBL4850658 | 0.79 | PIK3CD (0.61) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL28003501 | 0.78 | KMT2A (0.44) | ARKMT2APIK3CDPIK3CAPIK3CB | |
| SCHEMBL28003157 | 0.78 | CETP (0.46) | ARKMT2APIK3CDPIK3CAPIK3CB | |
| SCHEMBL16561758 | 0.76 | AR (0.55) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL15349299 | 0.75 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL15348861 | 0.74 | PIK3CD (0.52) | ARKMT2APIK3CDPIK3CAPIK3CB | |
| SCHEMBL4845510 | 0.72 | AR (0.51) | ARPIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL26051147 | 0.72 | AR (0.51) | ARKMT2APIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583218-A | Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | BRISTOL MYERS SQUIBB CO | 2015-04-29 | — | — | CN | disclosed |