Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603633 | 0.76 | HRH4 (0.59) | HRH4 | |
| SCHEMBL606337 | 0.76 | HRH4 (0.56) | HRH4 | |
| SCHEMBL23869413 | 0.76 | HRH4 (0.56) | HRH4 | |
| SCHEMBL4400403 | 0.75 | HRH4 (0.56) | HRH4 | |
| Hydrochloric Acid SCHEMBL21858185 | 0.75 | HRH4 (0.55) | HRH4 | |
| Hydrochloric Acid SCHEMBL23855365 | 0.75 | HRH4 (0.55) | HRH4 | |
| SCHEMBL606704 | 0.75 | HRH4 (0.57) | HRH4 | |
| SCHEMBL604007 | 0.74 | HRH4 (0.53) | HRH4 | |
| SCHEMBL606610 | 0.73 | HRH4 (0.61) | HRH4 | |
| SCHEMBL23869426 | 0.72 | HRH4 (0.56) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168077-A1 | Novel Pyridine Derivatives, Processes for Preparing Them, Pharmaceutical Compositions Thereof | UCB PHARMA, S.A. (BE) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168077-A1 | Novel Pyridine Derivatives, Processes for Preparing Them, Pharmaceutical Compositions Thereof | CYP4B1, CYP3A4, CYP2C19 | HRH4 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.