Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606337 | 0.85 | HRH4 (0.56) | HRH4 | |
| SCHEMBL602802 | 0.83 | HTR3A (0.45) | HRH4 | |
| SCHEMBL604007 | 0.83 | HRH4 (0.53) | HRH4 | |
| SCHEMBL606704 | 0.82 | HRH4 (0.57) | HRH4 | |
| SCHEMBL2801938 | 0.78 | HRH4 (0.52) | HRH4HRH3 | |
| SCHEMBL603634 | 0.77 | HRH4 (0.39) | HRH4HRH3 | |
| SCHEMBL2800355 | 0.76 | HRH4 (0.58) | HRH4 | |
| SCHEMBL23931297 | 0.76 | HRH4 (0.53) | HRH4 | |
| SCHEMBL30261134 | 0.76 | HRH4 (0.53) | HRH4 | |
| SCHEMBL23931299 | 0.76 | HRH4 (0.53) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9526725-B2 | Selective histamine H4 receptor antagonists for the treatment of vestibular disorders | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2016-12-27 | — | — | US | disclosed |
| US-20120039913-A1 | Selective Histamine H4 Receptor Antagonists for the Treatment of Vestibular Disorders | INSERM (institut National de la Sante de la Recher Medicale) (FR) | 2012-02-16 | — | — | US | disclosed |