Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798082 | 0.93 | F10 (0.43) | F10TOP2ATOP2BNISCHMAOA | |
| SCHEMBL2800383 | 0.82 | F10 (0.52) | F10TOP2ATOP2BNISCHGAA | |
| SCHEMBL2800498 | 0.76 | MAOA (0.41) | F10MAOA | |
| SCHEMBL2798085 | 0.74 | F10 (0.54) | F10TOP2ATOP2BNISCH | |
| SCHEMBL2796421 | 0.74 | MAOA (0.43) | F10MAOA | |
| SCHEMBL4753182 | 0.73 | F10 (0.67) | F10 | |
| SCHEMBL2800260 | 0.72 | MAOA (0.41) | F10MAOA | |
| SCHEMBL5762328 | 0.72 | GRM2 (0.53) | F10MAOA | |
| SCHEMBL13515441 | 0.71 | MAOA (0.55) | F10MAOAGAA | |
| SCHEMBL2798690 | 0.71 | GRM2 (0.52) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288423-B2 | FXa inhibitors with cyclic amidines as P4 subunit, processes for their preparations, and pharmaceutical compositions and derivatives thereof | LEGOCHEM BIOSCIENCE LTD. (KR) | 2012-10-16 | — | — | US | disclosed |
| US-20100184781-A1 | FXA INHIBITORS WITH CYCLIC AMIDINES AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184781-A1 | FXA INHIBITORS WITH CYCLIC AMIDINES AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF | F12, F2, TFPI | F10 4/4885TOP2A 3190/4885TOP2B 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.