SCHEMBL28004232

SCHEMBL28004232

CCCCCCCCc1ccc2c(c1)sc1cc(CCCCCCCC)ccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.48
ESR1 P03372 2/20 0.48
ADRA2A P08913 2/20 0.48
ADORA3 P0DMS8 2/20 0.48
TACR2 P21452 2/20 0.48
SLC6A2 P23975 2/20 0.48
SLC6A4 P31645 2/20 0.48
SLC6A3 Q01959 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
SHBG P04278 1/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
HSPD1 P10809 1/20 0.48
ADRB3 P13945 1/20 0.48
HTR2C P28335 1/20 0.48
HSPE1 P61604 1/20 0.48
HIF1A Q16665 1/20 0.48
TST Q16762 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18267841 0.95 ESR1 (0.43) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL18538778 0.91 PTGS2 (0.44) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL15497420 0.91 PTGS2 (0.44) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL709940 0.89 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL10031386 0.89 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL31318821 0.89 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL708808 0.89 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL18267822 0.89 ESR1 (0.42) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL15497378 0.89 ESR1 (0.42) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL30423034 0.89 PTGS2 (0.46) PTGS2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107540823-A One kind is based on S, the strong two-photon absorption conjugated polymer of S dioxydibenze bithiophene units and preparation method and application 华南理工大学 2018-01-05 CN disclosed
CN-106366067-A Blue oligomer based on dibenzothiophene-S,S-dioxide unit and preparation method and application of blue oligomer 华南理工大学 2017-02-01 CN disclosed
CN-101712674-B Alkyl substituted-S,S-dioxo-dibenzothiophene monomer, preparation method and polymer thereof UNIV SOUTH CHINA TECH 2015-03-11 CN disclosed