Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754710 | 0.92 | KDR (0.36) | KDR | |
| SCHEMBL16610857 | 0.92 | KDR (0.36) | KDR | |
| SCHEMBL28003791 | 0.88 | KDR (0.36) | KDR | |
| SCHEMBL28003796 | 0.83 | KDR (0.37) | KDR | |
| SCHEMBL28003915 | 0.83 | KDR (0.37) | KDR | |
| SCHEMBL16610807 | 0.80 | KDR (0.38) | KDR | |
| SCHEMBL16772657 | 0.80 | KDR (0.38) | KDR | |
| SCHEMBL16611019 | 0.76 | KDR (0.38) | KDR | |
| SCHEMBL28003809 | 0.76 | CFB (0.32) | — | |
| SCHEMBL16772652 | 0.75 | KDR (0.37) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470918-A | Aromatic heterocyclic derivative and pharmaceutical | NIPPON SHINYAKU CO LTD | 2015-03-25 | — | — | CN | claimed |
| CN-104470918-A | Aromatic heterocyclic derivative and pharmaceutical | NIPPON SHINYAKU CO LTD | 2015-03-25 | — | — | CN | disclosed |