SCHEMBL28003809

SCHEMBL28003809

CCc1c(O)nc(N2CCC[C@H]2c2ccc(CN)cc2)nc1COC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CFB P00751 1/20 0.32
AADAT Q8N5Z0 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16610540 0.89 MAOA (0.35) AADATALDH1A1
SCHEMBL28003803 0.80 DRD2 (0.36)
SCHEMBL28004247 0.76 KDR (0.34)
SCHEMBL16610660 0.76 CYP19A1 (0.36) ALDH1A1
SCHEMBL28003810 0.72 OPRK1 (0.34) CFBALDH1A1
SCHEMBL28003808 0.68 DRD2 (0.38) CFBAADAT
SCHEMBL16610534 0.67 ALDH1A1 (0.39) ALDH1A1
SCHEMBL16610681 0.67 ALDH1A1 (0.39) ALDH1A1
SCHEMBL28003814 0.66 JAK2 (0.37) CFB
SCHEMBL16610752 0.66 CYP19A1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104470918-A Aromatic heterocyclic derivative and pharmaceutical NIPPON SHINYAKU CO LTD 2015-03-25 CN disclosed