Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28004287 | 1.00 | MAPT (0.57) | MAPTKMT2AALDH1A1MEN1HSD17B10 | |
| SCHEMBL999789 | 0.97 | MAPT (0.61) | MAPTKMT2AALDH1A1MEN1HSD17B10 | |
| SCHEMBL1001481 | 0.88 | KMT2A (0.56) | MAPTKMT2AALDH1A1MEN1HSD17B10 | |
| SCHEMBL1001743 | 0.88 | KMT2A (0.56) | MAPTKMT2AALDH1A1MEN1HSD17B10 | |
| SCHEMBL999690 | 0.88 | POLB (0.54) | MAPTKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL28004746 | 0.87 | KMT2A (0.53) | MAPTKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL1000590 | 0.87 | KMT2A (0.51) | MAPTKMT2AALDH1A1MEN1HSD17B10 | |
| SCHEMBL1002268 | 0.85 | MAPT (0.55) | MAPTKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL1000614 | 0.83 | L3MBTL1 (0.76) | MAPTKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL1000582 | 0.82 | L3MBTL1 (0.59) | MAPTKMT2AALDH1A1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104352492-A | Long-chain fatty acyl elongase inhibitor comprising arylsulfonyl derivative as active ingredient | MSD KK | 2015-02-18 | — | — | CN | disclosed |