Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 4/20 | 0.78 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.69 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.69 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522707 | 1.00 | FTO (0.78) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL523829 | 1.00 | FTO (0.78) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL522706 | 1.00 | FTO (0.78) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL523083 | 0.89 | FTO (0.76) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL522082 | 0.89 | FTO (0.76) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL522083 | 0.89 | FTO (0.76) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL523475 | 0.88 | FTO (1.00) | FTOEGLN1BBOX1 | |
| SCHEMBL29619835 | 0.88 | FTO (1.00) | FTOEGLN1BBOX1 | |
| SCHEMBL523353 | 0.88 | FTO (1.00) | FTOEGLN1BBOX1 | |
| SCHEMBL523354 | 0.88 | FTO (1.00) | FTOEGLN1BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104427980-A | Treatment for high cholesterol | FIBROGEN INC | 2015-03-18 | — | — | CN | disclosed |