Fluoromethane

Fluoromethane

SCHEMBL28005017

CF.O=C(OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.62
LMNA P02545 2/20 0.61
F2 P00734 1/20 0.61
ALDH1A1 P00352 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
HSD17B10 Q99714 1/20 0.52
TP53 P04637 1/20 0.50
KMT2A Q03164 4/20 0.48
MAPT P10636 3/20 0.48
MAPK1 P28482 1/20 0.48
HIF1A Q16665 1/20 0.48
POLB P06746 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A3 Q01959 1/20 0.48
CES2 O00748 4/20 0.48
CES1 P23141 4/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL19514313 0.92 TSHR (0.65) TSHRLMNAF2ALDH1A1TDP1
Ethane SCHEMBL27444853 0.92 TSHR (0.65) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL52413 0.92 LMNA (0.70) TSHRLMNAF2ALDH1A1TDP1
Hydrogen Peroxide SCHEMBL27952375 0.92 LMNA (0.70) TSHRLMNAF2ALDH1A1TDP1
Benzene SCHEMBL27793442 0.92 LMNA (0.70) TSHRLMNAF2ALDH1A1TDP1
Acetic Acid SCHEMBL777098 0.90 TSHR (0.62) TSHRLMNAF2ALDH1A1TDP1
Methoxymethane SCHEMBL28409022 0.90 TSHR (0.70) TSHRLMNAF2ALDH1A1TDP1
Phosphine SCHEMBL9591710 0.90 LMNA (0.67) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL5314071 0.90 LMNA (0.67) TSHRLMNAF2ALDH1A1TDP1
SCHEMBL1534569 0.90 LMNA (0.67) TSHRLMNAF2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104370786-A Process and intermediates for the preparation of isomer free prostaglandins CHIROGATE INT INC 2015-02-25 CN disclosed