SCHEMBL28005103

SCHEMBL28005103

C#CCOCCSSCCOCC#C

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL664220 0.79
SCHEMBL9492835 0.78 TSHR (0.50) TSHR
SCHEMBL27190031 0.76 TSHR (0.48) TSHR
SCHEMBL22589673 0.76 TSHR (0.48) TSHR
SCHEMBL15800508 0.76 TSHR (0.48) TSHR
SCHEMBL12360400 0.76 TSHR (0.48) TSHR
SCHEMBL15803984 0.76 TSHR (0.48) TSHR
SCHEMBL15803986 0.76 TSHR (0.48) TSHR
SCHEMBL19122489 0.75
SCHEMBL7254965 0.73 TSHR (0.58) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240426831-A1 STRUCTURAL PROFILING OF NATIVE PROTEINS USING FLUOROSEQUENCING, A SINGLE MOLECULE PROTEIN SEQUENCING TECHNOLOGY UNIV TEXAS (US) 2024-12-26 US disclosed
EP-4469484-A1 COMBINATION THERAPY FOR CANCER GlaxoSmithKline Intellectual Property Development Ltd (GB) 2024-12-04 EP disclosed
CN-118591560-A Combination therapy for cancer 葛兰素史密斯克莱知识产权发展有限公司 2024-09-03 CN disclosed
WO-2023144702-A1 COMBINATION THERAPY FOR CANCER GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-08-03 WO disclosed
CN-104487481-B Block copolymers for stable micelles 茵肽锌科技公司 2016-11-16 CN disclosed
CN-104487481-A Block copolymers for stable micelles INTEZYNE TECHNOLOGIES INC 2015-04-01 CN disclosed