SCHEMBL28005115

SCHEMBL28005115

[CH2]C(C)C(O)OC(=O)C=C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.43
HPGD P15428 1/20 0.38
ALDH1A1 P00352 4/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1373352 0.84 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1092841 0.84 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL30938817 0.83 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8965801 0.82 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27617064 0.82 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8965588 0.80 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8965566 0.80 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11308785 0.80 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27402151 0.79 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8965559 0.78 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105473628-B Adhesion enhancing additives and coating compositions containing the same 比克化学股份有限公司 2019-04-12 CN claimed
CN-105473628-A Adhesion enhancing additives and coating compositions containing the same BYK CHEMIE GMBH 2016-04-06 CN claimed
CN-105473628-B Adhesion enhancing additives and coating compositions containing the same 比克化学股份有限公司 2019-04-12 CN disclosed
CN-104418958-B The manufacture method of organic mineral complex, solidification compound and solidfied material thereof, firmly it is coated with material, hard coat film and silane coupler 昭和电工株式会社 2016-07-06 CN disclosed
CN-105473628-A Adhesion enhancing additives and coating compositions containing the same BYK CHEMIE GMBH 2016-04-06 CN disclosed
CN-104418958-A Preparation method of organic mineral complex, curable composition, cured product of curable composition, hard coating material, hard coating film and silane coupling agent SHOWA DENKO KK 2015-03-18 CN disclosed
CN-104419234-A Cured composition, cured product thereof, hard primer and hard coating SHOWA DENKO KK 2015-03-18 CN disclosed