Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.65 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.65 |
| ▸ | THRA | P10827 | 8/20 | 0.62 |
| ▸ | THRB | P10828 | 8/20 | 0.62 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.48 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523801 | 0.88 | THRA (0.79) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522183 | 0.88 | EGLN1 (0.64) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523787 | 0.86 | EGLN1 (0.58) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1656039 | 0.84 | EGLN1 (0.55) | EGLN1EGLN2 | |
| SCHEMBL522169 | 0.84 | EGLN1 (0.70) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523965 | 0.84 | THRA (0.72) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL966797 | 0.84 | EGLN1 (0.73) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523594 | 0.81 | EGLN1 (0.70) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522230 | 0.81 | EGLN1 (0.70) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1270194 | 0.81 | EGLN1 (0.69) | EGLN1BBOX1FTOTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104427980-A | Treatment for high cholesterol | FIBROGEN INC | 2015-03-18 | — | — | CN | disclosed |