Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27976864 | 0.84 | CA12 (0.44) | KDM4EHPGDALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28639867 | 0.77 | GABRA1 (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28267255 | 0.76 | NPSR1 (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16498192 | 0.74 | HPGD (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27393841 | 0.73 | CYP2C9 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9513741 | 0.72 | CA12 (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5820404 | 0.72 | GABRA1 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL460319 | 0.72 | HTT (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10465784 | 0.70 | TSHR (0.47) | DPP4KDM4EHPGDALDH1A1TSHR | |
| SCHEMBL27950693 | 0.70 | HCAR2 (0.41) | KDM4EHPGDALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759516-A | A kind of preparation method of the dicarboxylic acid derivatives of alkyl ether substituted pyridines 2,3 | 沈阳化工研究院有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-104447527-A | Method for preparing pyridine-2,3-dicarboxylic ester compound | SINOCHEM CORP | 2015-03-25 | — | — | CN | disclosed |