Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | USP14 | P54578 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | USP7 | Q93009 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | USP5 | P45974 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23524551 | 0.99 | SMN1; SMN2 (0.76) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL28005478 | 0.89 | SMN1; SMN2 (0.72) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL23524514 | 0.89 | USP14 (0.70) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL17949750 | 0.88 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL6922583 | 0.86 | SMN1; SMN2 (0.97) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL28005476 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL23524553 | 0.85 | SMN1; SMN2 (0.81) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL16079020 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL23524510 | 0.84 | SMN1; SMN2 (0.83) | SMN1; SMN2HPGDUSP14KDM4EUSP7 | |
| SCHEMBL6921679 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDUSP14KDM4EUSP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478780-A | Acylpyrrole small-molecular organic compound, derivatives of organic compound as well as application and preparation method of acylpyrrole small-molecular organic compound and derivatives of organic compound | UNIV EAST CHINA NORMAL | 2015-04-01 | — | — | CN | claimed |
| CN-104478780-A | Acylpyrrole small-molecular organic compound, derivatives of organic compound as well as application and preparation method of acylpyrrole small-molecular organic compound and derivatives of organic compound | UNIV EAST CHINA NORMAL | 2015-04-01 | — | — | CN | disclosed |