SCHEMBL28005667

SCHEMBL28005667

C=Cc1cc(C(=O)O)cc(C(=O)O)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A8 Q8TCC7 4/20 0.47
SLC22A6 Q4U2R8 3/20 0.44
TPMT P51580 2/20 0.42
KDM4E B2RXH2 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HCAR1 Q9BXC0 1/20 0.37
GPR35 Q9HC97 1/20 0.37
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
CASP6 P55212 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3097749 0.80 TPMT (0.56) TPMTKDM4ETDP1MEN1KMT2A
SCHEMBL22555845 0.79 SLC22A8 (0.38) SLC22A8SLC22A6TPMTKDM4ETDP1
Fluoride SCHEMBL11641082 0.78 TPMT (0.54) TPMTKDM4ETDP1MEN1KMT2A
SCHEMBL27489414 0.74 TPMT (0.47) SLC22A8SLC22A6TPMTKDM4EHCAR1
SCHEMBL71249 0.74 TPMT (0.50) TPMTKDM4ETDP1MEN1KMT2A
SCHEMBL22882559 0.74 CA12 (0.41) SLC22A8SLC22A6TPMTKDM4ETDP1
SCHEMBL30424047 0.73 KDM4E (0.47) SLC22A8SLC22A6KDM4ETDP1MEN1
SCHEMBL605638 0.73 KDM4E (0.47) SLC22A8SLC22A6KDM4ETDP1POLB
SCHEMBL5484317 0.73 KDM4E (0.47) SLC22A8SLC22A6KDM4ETDP1MEN1
SCHEMBL29598455 0.73 KDM4E (0.47) SLC22A8SLC22A6KDM4ETDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104837973-A Fragrance materials PROCTER & GAMBLE 2015-08-12 CN claimed
CN-104837478-A Personal care compositions PROCTER & GAMBLE 2015-08-12 CN claimed
CN-104837973-A Fragrance materials PROCTER & GAMBLE 2015-08-12 CN disclosed
CN-104837478-A Personal care compositions PROCTER & GAMBLE 2015-08-12 CN disclosed