SCHEMBL5484317

SCHEMBL5484317

C=Cc1ccc(C(=O)O)cc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
TDP1 Q9NUW8 4/20 0.43
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
GAA P10253 2/20 0.42
POLB P06746 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MAPT P10636 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
PTGS2 P35354 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
PTPN1 P18031 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30424047 1.00 KDM4E (0.47) KDM4ETDP1TSHRTP53L3MBTL1
SCHEMBL29598455 0.84 KDM4E (0.47) KDM4ETDP1TSHRTP53L3MBTL1
SCHEMBL605638 0.84 KDM4E (0.47) KDM4ETDP1TSHRTP53L3MBTL1
Lithium SCHEMBL31456603 0.82 KDM4E (0.46) KDM4ETDP1TSHRTP53L3MBTL1
SCHEMBL3040058 0.82 ERN1 (0.49) KDM4ETDP1TSHRTP53L3MBTL1
SCHEMBL28190707 0.80 MCL1 (0.45) TDP1PTGS2PTPN1HSD17B10ALDH1A1
SCHEMBL28596875 0.80 CA12 (0.55) TDP1TSHRL3MBTL1GAAPOLB
SCHEMBL27523131 0.80 KDM4E (0.47) KDM4ETDP1TSHRTP53L3MBTL1
SCHEMBL20769195 0.80 CA12 (0.57) KDM4ETDP1TSHRTP53L3MBTL1
SCHEMBL31566098 0.78 CDC25B (0.46) KDM4ETDP1TSHRTP53L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4353759-A1 PRODUCTION METHOD FOR AQUEOUS FLUORINE-CONTAINING ELASTOMER DISPERSION, COMPOSITION, AND AQUEOUS DISPERSION Daikin Industries, Ltd. (JP) 2024-04-17 EP disclosed
CN-117529511-A Method for producing aqueous dispersion of fluoroelastomer, composition, and aqueous dispersion 大金工业株式会社 2024-02-06 CN disclosed
US-20230192924-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION AND FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION DAIKIN INDUSTRIES, LTD. (JP) 2023-06-22 US disclosed
EP-4194474-A1 METHOD FOR PRODUCING AQUEOUS DISPERSION OF FLUORINE-CONTAINING ELASTOMER Daikin Industries, Ltd. (JP) 2023-06-14 EP disclosed
EP-4186932-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION AND FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION Daikin Industries, Ltd. (JP) 2023-05-31 EP disclosed
CN-116171291-A Method for producing aqueous dispersion of fluoroelastomer, and aqueous dispersion of fluoroelastomer 大金工业株式会社 2023-05-26 CN disclosed
WO-2022260139-A1 PRODUCTION METHOD FOR AQUEOUS FLUORINE-CONTAINING ELASTOMER DISPERSION, COMPOSITION, AND AQUEOUS DISPERSION ダイキン工業株式会社 2022-12-15 WO disclosed
US-11326006-B2 Organic thin-film transistor and polymer compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-10 US disclosed
WO-2022030389-A1 METHOD FOR PRODUCING AQUEOUS DISPERSION OF FLUORINE-CONTAINING ELASTOMER ダイキン工業株式会社 2022-02-10 WO disclosed
WO-2022019241-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION AND FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION ダイキン工業株式会社 2022-01-27 WO disclosed
US-7220780-B2 Naaladase inhibitors for treating retinal disorders and glaucoma GUILFORD PHARMACEUTICALS INC. (US) 2007-05-22 US disclosed
US-20050171065-A1 NAALADas, N-Acetylated-Alpha-Linked-Acidic-Dipeptidase inhibitors; 5-phosphonomethyl-1,3-benzenedicarboxylic Acid; glutamate abnormalities, anticancer, antidiabetic agent, angiogenesis inhibitor, neuropathy, pain, compulsive disorders, prostate diseases, glaucoma GUILFORD PHARMACEUTICALS INC. 2005-08-04 US disclosed
US-20050080139-A1 Naaladase inhibitors for treating huntington's disease GUILFORD PHARMACEUTICALS INC. 2005-04-14 US disclosed
US-20030036534-A1 Naaladase inhibitors for treating retinal disorders and glaucoma EISAI INC. 2003-02-20 US disclosed
US-6452044-B2 NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS GUILFORD PHARMACEUTICALS INC. 2002-09-17 US disclosed
US-20020019430-A1 Nervous system and psychological disorders EISAI INC. 2002-02-14 US disclosed
US-20020013295-A1 Naaladase inhibitors for treating amyotrophic lateral sclerosis GUILFORD PHARMACEUTICALS INC., A DELAWARE CORPORATION 2002-01-31 US disclosed
CN-1205698-A Heterocyclyl-condensed benzoylguanidines, their prodn. and use as inhibitors of cellular Na+/H+-antiporter MERCK PATENT GES MIT BESCHR KT (DE) 1999-01-20 CN disclosed
WO-1996034851-A1 BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE ABBOTT LABORATORIES (US) 1996-11-07 WO disclosed
US-4042750-A COATINGS, MOLDING MATERIALS STANDARD OIL COMPANY (INDIANA) (US) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013295-A1 Naaladase inhibitors for treating amyotrophic lateral sclerosis SMN1; SMN2, GAA, NAALAD2 KDM4E 1863/4885TDP1 62/4885TSHR 4825/4885
US-20050080139-A1 Naaladase inhibitors for treating huntington's disease HTT, GAA, ADA KDM4E 2554/4885TDP1 27/4885TSHR 3380/4885
US-20050171065-A1 NAALADas, N-Acetylated-Alpha-Linked-Acidic-Dipeptidase inhibitors; 5-phosphonomethyl-1,3-benzenedicarboxylic Acid; glutamate abnormalities, anticancer, antidiabetic agent, angiogenesis inhibitor, neuropathy, pain, compulsive disorders, prostate diseases, glaucoma NAALAD2, GLUL, DNPEP KDM4E 3314/4885TDP1 296/4885TSHR 4610/4885
US-20020019430-A1 Nervous system and psychological disorders GLUL, DDC, DNPEP KDM4E 2369/4885TDP1 533/4885TSHR 4664/4885
US-20030036534-A1 Naaladase inhibitors for treating retinal disorders and glaucoma ALDH1A2, GAA, PDE6A KDM4E 2355/4885TDP1 125/4885TSHR 3404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.