Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243820 | 0.90 | HSD17B10 (0.48) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL29642762 | 0.88 | HSD17B10 (0.46) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL429572 | 0.88 | HSD17B10 (0.46) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL15123411 | 0.88 | HSD17B10 (0.46) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL5719995 | 0.88 | HSD17B10 (0.46) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL16225047 | 0.85 | MYC (0.45) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL31621734 | 0.78 | CYP3A4 (0.53) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL6321350 | 0.76 | CYP3A4 (0.52) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL28459376 | 0.76 | HPRT1 (0.56) | HPRT1HSD17B10ALDH1A1TDP1CYP2A6 | |
| SCHEMBL8840923 | 0.75 | MYC (0.37) | HPRT1HSD17B10ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104387381-A | Drug application of hydroxyl phenanthroquinolizidine derivatives | SHANGHAI YIZHI MEDICINE TECHNOLOGY CO LTD | 2015-03-04 | — | — | CN | claimed |
| CN-104387381-A | Drug application of hydroxyl phenanthroquinolizidine derivatives | SHANGHAI YIZHI MEDICINE TECHNOLOGY CO LTD | 2015-03-04 | — | — | CN | disclosed |