SCHEMBL8840923

SCHEMBL8840923

Oc1ccc2c(n1)c1ccc(O)nc1c1ccc(O)nc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.37
MAX P61244 1/20 0.37
KMT2A Q03164 2/20 0.33
OPRK1 P41145 1/20 0.33
MAPT P10636 3/20 0.32
RAB9A P51151 3/20 0.32
GAA P10253 2/20 0.32
ALDH1A1 P00352 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CYP1A2 P05177 2/20 0.32
IDO1 P14902 1/20 0.32
ACHE P22303 1/20 0.31
HPRT1 P00492 1/20 0.30
KDM4E B2RXH2 2/20 0.30
NPC1 O15118 2/20 0.30
LMNA P02545 2/20 0.30
MITF O75030 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
AGTR1 P30556 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16225047 0.89 MYC (0.45) MYCMAXKMT2AMAPTRAB9A
SCHEMBL6844002 0.78 CCR1 (0.43) KMT2AMAPTRAB9AALDH1A1CYP1A2
SCHEMBL243820 0.75 HSD17B10 (0.48) MAPTRAB9AGAAALDH1A1CYP1A2
SCHEMBL5719995 0.73 HSD17B10 (0.46) MAPTRAB9AGAAALDH1A1CYP1A2
SCHEMBL29642762 0.73 HSD17B10 (0.46) MAPTRAB9AGAAALDH1A1CYP1A2
SCHEMBL429572 0.73 HSD17B10 (0.46) MAPTRAB9AGAAALDH1A1CYP1A2
SCHEMBL15123411 0.73 HSD17B10 (0.46) KMT2AMAPTRAB9AALDH1A1CYP1A2
SCHEMBL12733228 0.72 ADORA3 (0.49) MYCMAXKMT2AMAPTRAB9A
SCHEMBL29128827 0.70
SCHEMBL17265898 0.69 KDM4E (0.32) MAPTALDH1A1KDM4ELMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5637669-A THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-06-10 US disclosed
EP-0670856-A1 THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP disclosed
WO-1994012556-A2 THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO disclosed