Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201709 | 1.00 | GAA (0.55) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8493745 | 0.74 | KDM4E (0.64) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8493749 | 0.74 | KDM4E (0.64) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2800046 | 0.73 | KDM4E (0.60) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2802250 | 0.73 | KMT2A (0.64) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL13201844 | 0.73 | KDM4E (0.60) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3463211 | 0.72 | NPC1 (0.60) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3463212 | 0.72 | NPC1 (0.60) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3066581 | 0.71 | NPC1 (0.62) | GAANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3066579 | 0.71 | NPC1 (0.62) | GAANPC1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100209537-A1 | Metal complexes with anticancer activity | BANGALORE RAMESH | 2010-08-19 | — | — | US | disclosed |