Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | HTT | P42858 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800046 | 1.00 | KDM4E (0.60) | KDM4EMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL2802250 | 0.74 | KMT2A (0.64) | KDM4EMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL2800637 | 0.73 | GAA (0.55) | KDM4EMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL13201709 | 0.73 | GAA (0.55) | KDM4EMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL28170008 | 0.73 | PAX8 (0.58) | KDM4EMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1164645 | 0.72 | PAX8 (1.00) | KDM4EMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1164644 | 0.72 | PAX8 (1.00) | KDM4EMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29692738 | 0.72 | PAX8 (1.00) | KDM4EMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL28952987 | 0.72 | PAX8 (0.70) | KDM4EMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8342118 | 0.72 | PAX8 (0.65) | KDM4EMAPTHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100209537-A1 | Metal complexes with anticancer activity | BANGALORE RAMESH | 2010-08-19 | — | — | US | disclosed |