Fluoride

Fluoride

SCHEMBL28006458

C=CC=Cc1ccccc1.F

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.65
ALDH1A1 P00352 4/20 0.54
MAPK1 P28482 2/20 0.54
LMNA P02545 2/20 0.54
TRPA1 O75762 1/20 0.54
ALOX5 P09917 1/20 0.54
TSHR P16473 1/20 0.50
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45
MAPT P10636 2/20 0.45
RECQL P46063 2/20 0.45
POLB P06746 1/20 0.45
CMA1 P23946 1/20 0.43
CYP3A4 P08684 1/20 0.42
NFE2L2 Q16236 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAOA P21397 1/20 0.42
HDAC3 O15379 2/20 0.42
HDAC4 P56524 2/20 0.42
HDAC1 Q13547 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33879 0.97 MAOB (0.68) MAOBALDH1A1MAPK1LMNATRPA1
SCHEMBL93419 0.97 MAOB (0.68) MAOBALDH1A1MAPK1LMNATRPA1
SCHEMBL4936136 0.97 MAOB (0.68) MAOBALDH1A1MAPK1LMNATRPA1
SCHEMBL27481341 0.97 MAOB (0.68) MAOBALDH1A1MAPK1LMNATRPA1
Ammonia Solution, Strong SCHEMBL1374279 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
Hydrochloric Acid SCHEMBL10895547 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
Butadiene SCHEMBL372392 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
SCHEMBL29695867 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
Iodide SCHEMBL7637898 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
Ethylene SCHEMBL27660169 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104619682-A Polyisocyanate composition and isocyanate polymer composition ASAHI KASEI CHEMICALS CORP 2015-05-13 CN disclosed