Butadiene

Butadiene

SCHEMBL372392

C=CC=C.C=CC=Cc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.65
ALDH1A1 P00352 4/20 0.54
MAPK1 P28482 2/20 0.54
LMNA P02545 2/20 0.54
TRPA1 O75762 1/20 0.54
ALOX5 P09917 1/20 0.54
TSHR P16473 1/20 0.50
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45
MAPT P10636 2/20 0.45
RECQL P46063 2/20 0.45
POLB P06746 1/20 0.45
CMA1 P23946 1/20 0.43
CYP3A4 P08684 1/20 0.42
NFE2L2 Q16236 1/20 0.42
CYP19A1 P11511 1/20 0.42
MAOA P21397 1/20 0.42
HDAC3 O15379 2/20 0.42
HDAC4 P56524 2/20 0.42
HDAC1 Q13547 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33879 0.97 MAOB (0.68) MAOBALDH1A1MAPK1LMNATRPA1
SCHEMBL27481341 0.97 MAOB (0.68) MAOBALDH1A1MAPK1LMNATRPA1
SCHEMBL93419 0.97 MAOB (0.68) MAOBALDH1A1MAPK1LMNATRPA1
SCHEMBL4936136 0.97 MAOB (0.68) MAOBALDH1A1MAPK1LMNATRPA1
Ammonia Solution, Strong SCHEMBL1374279 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
SCHEMBL29695867 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
Fluoride SCHEMBL28006458 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
Iodide SCHEMBL7637898 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
Hydrochloric Acid SCHEMBL10895547 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1
Benzene SCHEMBL27881057 0.95 MAOB (0.65) MAOBALDH1A1MAPK1LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773528-B Vinyl styrene-butadiene latex and preparation method and application thereof 山东京博中聚新材料有限公司 2024-01-19 CN claimed
CN-115850617-A High-vinyl SBS modifier and preparation method thereof 青岛科凯达橡塑有限公司 2023-03-28 CN claimed
CN-114773528-A Vinyl styrene-butadiene latex and preparation method and application thereof 山东京博中聚新材料有限公司 2022-07-22 CN claimed
US-20160244471-A1 PHENOXYCYCLOTRIPHOSPHAZENE ACTIVE ESTER, HALOGEN-FREE RESIN COMPOSITION AND USES THEREOF SHENGYI TECHNOLOGY CO., LTD. (CN) 2016-08-25 US claimed
EP-3037475-A1 PHENOXY CYCLOTRIPHOSPHAZENE ACTIVE ESTER, HALOGEN-FREE RESIN COMPOSITION AND USE THEREOF Shengyi Technology Co., Ltd. (CN) 2016-06-29 EP claimed
EP-2964706-A1 THREADED TUBULAR COMPONENT PROTECTED BY A FILM VALLOUREC OIL AND GAS FRANCE (FR) 2016-01-13 EP claimed
US-20160002476-A1 THREADED TUBULAR COMPONENT PROTECTED BY A FILM VALLOUREC OIL AND GAS FRANCE (FR) 2016-01-07 US claimed
WO-2014135499-A1 THREADED TUBULAR COMPONENT PROTECTED BY A FILM VALLOUREC OIL AND GAS FRANCE (FR) 2014-09-12 WO claimed
EP-1692230-B1 RAPID DISPERSING HYDROUS KAOLINS IMERYS KAOLIN INC (US) 2008-12-31 EP claimed
US-20070161736-A1 Rapid dispersing hydrous kaolins IMERYS KAOLIN, INC. 2007-07-12 US claimed
EP-1692230-A2 RAPID DISPERSING HYDROUS KAOLINS Imerys Kaolin, Inc. (US) 2006-08-23 EP claimed
WO-2005052066-A2 RAPID DISPERSING HYDROUS KAOLINS IMERYS KAOLIN, INC. (US) 2005-06-09 WO claimed
US-6245861-B1 CONTROLLING CONCENTRATION HERCULES INCORPORATED 2001-06-12 US claimed
US-6080809-A DECREASING STRAIN MODULUS WITHOUT DECREASING HARDNESS IN SILICA TREAD COMPOUNDS IN RUBBER TIRES BRIDGESTONE/FIRESTONE, INC. (US) 2000-06-27 US claimed
US-4789430-A DIMENSIONAL STABILITY; RESISTANCE TO DELAMINATION ARJOMARI-PRIOUX (FR) 1988-12-06 US claimed
JP-9227723-A None JP disclosed
CN-115028787-B Polar modifier system for high vinyl block copolymerization 戴纳索尔伊莱斯托米罗斯公司 2024-06-11 CN disclosed
US-4669518-A Tire tread having high trans butadiene based elastomeric block copolymers and blends GENCORP INC. (US) 1987-06-02 US disclosed
US-4616065-A COPOLYMER OF STYRENE OR ISOPRENE; TIRE TREADS GENCORP INC. (US) 1986-10-07 US disclosed
US-4370448-A Thermosetting composition combined high vinyl diolefin polymer with high vinyl low vinyl diolefin polymer PHILLIPS PETROLEUM COMPANY (US) 1983-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244471-A1 PHENOXYCYCLOTRIPHOSPHAZENE ACTIVE ESTER, HALOGEN-FREE RESIN COMPOSITION AND USES THEREOF PFAS, PGLS, ELL MAOB 3664/4885ALDH1A1 2788/4885MAPK1 992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.