SCHEMBL28006649

SCHEMBL28006649

CCC[C@H]1CC[C@H](C=Cc2ccccc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.47
MAOB P27338 1/20 0.47
KDM1A O60341 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626610 1.00 MAOA (0.47) MAOAMAOBKDM1A
SCHEMBL28082291 1.00 MAOA (0.47) MAOAMAOBKDM1A
SCHEMBL28082289 1.00 MAOA (0.47) MAOAMAOBKDM1A
SCHEMBL9180238 0.89 MAOA (0.43) MAOAMAOB
SCHEMBL9180243 0.89 MAOA (0.43) MAOAMAOB
SCHEMBL27935712 0.85 MAOB (0.50) MAOAMAOB
SCHEMBL8748018 0.82 MAOB (0.53) MAOAMAOB
SCHEMBL27904620 0.82 MAOB (0.53) MAOAMAOB
SCHEMBL7725230 0.82 CYP2C9 (0.45) MAOB
SCHEMBL7725220 0.82 CYP2C9 (0.45) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103922886-B A kind of synthetic method of 1-fluoro-3-[2-(trans-4-alkyl-cyclohexyl) ethyl] benzene SHAANXI NORMAL UNIVERSITY (CN) 2015-08-19 CN disclosed