SCHEMBL28007398

SCHEMBL28007398

CCCCCCCCCCCCCCCCn1c2ccccc2c2ccc(C(C)=O)cc21

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 10/20 0.64
PSEN1 P49768 9/20 0.62
PSEN2 P49810 9/20 0.62
APH1B Q8WW43 9/20 0.62
NCSTN Q92542 9/20 0.62
APH1A Q96BI3 9/20 0.62
PSENEN Q9NZ42 9/20 0.62
CNR1 P21554 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28007691 1.00 CNR2 (0.64) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL28007695 0.95 CNR2 (0.60) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL28050793 0.92 CNR2 (0.75) CNR2CNR1
SCHEMBL28053878 0.92 CNR2 (0.75) CNR2CNR1
SCHEMBL28050803 0.92 CNR2 (0.75) CNR2CNR1
SCHEMBL28394599 0.92 CNR2 (0.75) CNR2CNR1
SCHEMBL28386085 0.92 CNR2 (0.75) CNR2CNR1
SCHEMBL27832072 0.92 CNR2 (0.75) CNR2CNR1
SCHEMBL28050802 0.91 CNR2 (0.77) CNR2CNR1
SCHEMBL14292119 0.88 ALDH1A1 (0.56) CNR2PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447506-A Preparation method of 2-acetyl-9-alkyl carbazole QINGHAI INST SALT LAKES CAS 2015-03-25 CN disclosed