SCHEMBL28007491

SCHEMBL28007491

O=C(c1cccc2ocnc12)c1cccc2ocnc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 2/20 0.47
NR4A2 P43354 1/20 0.36
DHODH Q02127 1/20 0.36
HCRTR2 O43614 1/20 0.35
CTNNB1 P35222 4/20 0.35
WNT3A P56704 4/20 0.35
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
GAA P10253 2/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
PARP1 P09874 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
XDH P47989 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL984268 0.87 PIN1 (0.52) PIN1NR4A2DHODHALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL27755478 0.85 PIN1 (0.51) PIN1NR4A2DHODHALDH1A1SMN1; SMN2
SCHEMBL854498 0.85 PARP1 (0.50) PIN1ALDH1A1PARP1ADORA2A
SCHEMBL15897691 0.85 PIN1 (0.45) PIN1NR4A2DHODHHCRTR2CTNNB1
SCHEMBL2009467 0.85 PIN1 (0.42) PIN1NR4A2DHODHHCRTR2CTNNB1
SCHEMBL27755564 0.85 PIN1 (0.51) PIN1NR4A2DHODHALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL27928599 0.85 PIN1 (0.51) PIN1NR4A2DHODHALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL28771898 0.84 PARP1 (0.49) PIN1ALDH1A1PARP1ADORA2A
Hydrochloric Acid SCHEMBL27755480 0.84 PARP1 (0.49) PIN1ALDH1A1PARP1ADORA2A
Hydrochloric Acid SCHEMBL27755490 0.82 PARP1 (0.47) PIN1ALDH1A1PARP1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104610186-A Method for purifying amino benzoxazinone crude product and preparation method of flumioxazin NUTRICHEM CO LTD 2015-05-13 CN disclosed