⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651684 | 0.80 | — | — | |
| SCHEMBL27891181 | 0.76 | — | — | |
| SCHEMBL27472036 | 0.75 | — | — | |
| SCHEMBL27778162 | 0.75 | OAT (0.30) | — | |
| SCHEMBL27597280 | 0.75 | — | — | |
| SCHEMBL27311616 | 0.75 | OAT (0.30) | — | |
| SCHEMBL28126056 | 0.75 | — | — | |
| SCHEMBL27835631 | 0.73 | — | — | |
| SCHEMBL27513460 | 0.72 | — | — | |
| SCHEMBL28149408 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061963-A | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-104507928-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-104918945-A | Tricyclic fused thiophene derivatives as JAK inhibitors | INCYTE CORP | 2015-09-16 | — | — | CN | disclosed |
| CN-104507928-A | Heterocyclic modulators of lipid synthesis | 3 V BIOSCIENCES INC | 2015-04-08 | — | — | CN | disclosed |