Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.54 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 11/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931200 | 0.85 | KIF11 (0.42) | KIF11MEN1MAPTKMT2APARP14 | |
| SCHEMBL442417 | 0.85 | KIF11 (0.53) | KIF11PIM1PIM3PIM2MEN1 | |
| SCHEMBL29394785 | 0.84 | KIF11 (0.53) | KIF11AHRPARP14 | |
| SCHEMBL187300 | 0.84 | KIF11 (0.53) | KIF11AHRPARP14 | |
| SCHEMBL867558 | 0.82 | KIF11 (0.52) | KIF11PARP14 | |
| SCHEMBL30950767 | 0.82 | KIF11 (0.52) | KIF11PARP14 | |
| SCHEMBL1071406 | 0.81 | KIF11 (0.50) | KIF11PARP14HPGDMAPK1HTT | |
| SCHEMBL29470863 | 0.81 | KIF11 (0.50) | KIF11PARP14 | |
| SCHEMBL29935623 | 0.79 | KIF11 (0.55) | KIF11AHRPARP14 | |
| SCHEMBL191031 | 0.79 | CDK4 (0.55) | KIF11PARP14HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104497013-B | Azepine carbazoles OLED material and preparation method and application | 石家庄诚志永华显示材料有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-104497013-A | Aza carbazole OLED (organic light emitting diode) material as well as preparation method and application thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD | 2015-04-08 | — | — | CN | disclosed |