Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28007668

N.O=C(O)c1ncc(Cl)c(Cl)c1Cl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.46
MEN1 O00255 3/20 0.46
KDM4E B2RXH2 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
POLB P06746 1/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 4/20 0.42
TDP1 Q9NUW8 4/20 0.42
HPGD P15428 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 2/20 0.41
MAPT P10636 3/20 0.40
HTT P42858 2/20 0.40
ATM Q13315 1/20 0.39
HSP90AA1 P07900 1/20 0.37
GAA P10253 1/20 0.37
NAPRT Q6XQN6 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
RXFP1 Q9HBX9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL632805 0.98 KMT2A (0.47) KMT2AMEN1KDM4ESMN1; SMN2POLB
SCHEMBL28816925 0.96 KMT2A (0.46) KMT2AMEN1KDM4ESMN1; SMN2POLB
Phenol SCHEMBL27853657 0.85 ATM (0.43) KMT2AMEN1KDM4ESMN1; SMN2POLB
SCHEMBL21582019 0.81 KMT2A (0.44) KMT2AMEN1KDM4ESMN1; SMN2POLB
SCHEMBL31071678 0.81 MEN1 (0.44) KMT2AMEN1KDM4ESMN1; SMN2POLB
SCHEMBL28984987 0.81 MEN1 (0.44) KMT2AMEN1KDM4ESMN1; SMN2POLB
SCHEMBL27963462 0.81 KMT2A (0.44) KMT2AMEN1KDM4ESMN1; SMN2POLB
SCHEMBL27503175 0.80 SMN1; SMN2 (0.45) KMT2AMEN1KDM4ESMN1; SMN2POLB
SCHEMBL25270186 0.79 KMT2A (0.43) KMT2AMEN1KDM4ESMN1; SMN2POLB
SCHEMBL1424615 0.79 TDP1 (0.50) KMT2AMEN1KDM4ESMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106854178-B A method of separating and recovering picloram from picloram ammonium salt waste residue 湖南比德生化科技股份有限公司 2019-04-30 CN claimed
CN-104649965-B The preparation method of 3,4,5,6-4 chloro pyridine formic acid Hunan Bhide biochemical technology company limited (CN) 2016-02-24 CN claimed
CN-104649965-A Preparation method of 3,4,5,6-tetrachloropyridine-2-carboxylic acid HUNAN BIDE BIOTECHNOLOGY CO LTD 2015-05-27 CN claimed
CN-106854178-B A method of separating and recovering picloram from picloram ammonium salt waste residue 湖南比德生化科技股份有限公司 2019-04-30 CN disclosed
CN-104649965-B The preparation method of 3,4,5,6-4 chloro pyridine formic acid Hunan Bhide biochemical technology company limited (CN) 2016-02-24 CN disclosed
CN-104628635-B A kind ofly produce separating-purifying waste residue from picloram and go out the method for high-content picloram Hunan Bhide biochemical technology company limited (CN) 2016-02-10 CN disclosed
CN-104649965-A Preparation method of 3,4,5,6-tetrachloropyridine-2-carboxylic acid HUNAN BIDE BIOTECHNOLOGY CO LTD 2015-05-27 CN disclosed
CN-104628635-A Method for separating and purifying high-content picloram from picloram production waste residues HUNAN BIDE BIOTECHNOLOGY CO LTD 2015-05-20 CN disclosed