Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.44 |
| ▸ | AKT2 | P31751 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008709 | 0.83 | MEN1 (0.37) | PDE10AMEN1KMT2ATP53POLB | |
| SCHEMBL1625166 | 0.82 | MEN1 (0.47) | AKT1AKT2PDE10AMEN1KMT2A | |
| SCHEMBL1625204 | 0.82 | AKT1 (0.51) | AKT1AKT2PDE10AMEN1KMT2A | |
| SCHEMBL27600116 | 0.81 | AKT1 (0.48) | AKT1AKT2PDE10AMEN1KMT2A | |
| SCHEMBL28008295 | 0.81 | MEN1 (0.41) | AKT1AKT2PDE10AMEN1KMT2A | |
| SCHEMBL27600254 | 0.77 | NTRK1 (0.47) | PDE10AMEN1KMT2ATP53POLB | |
| SCHEMBL27600149 | 0.76 | GSR (0.40) | PDE10ATP53SMN1; SMN2 | |
| SCHEMBL27582833 | 0.76 | PDE10A (0.39) | PDE10AKMT2ATP53 | |
| SCHEMBL27582863 | 0.76 | BMI1 (0.39) | PDE10APOLBPDPK1 | |
| SCHEMBL27582767 | 0.76 | PDE10A (0.39) | PDE10ATP53PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101967146-B | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents | RAQUALIA PHARMA INC | 2015-04-08 | — | — | CN | disclosed |