Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008295 | 0.84 | MEN1 (0.41) | MEN1KMT2ATP53POLBPABPC1 | |
| SCHEMBL28008294 | 0.83 | AKT1 (0.44) | MEN1KMT2ATP53POLBPABPC1 | |
| SCHEMBL1623518 | 0.82 | MEN1 (0.40) | MEN1KMT2ATP53POLBPABPC1 | |
| SCHEMBL1624761 | 0.82 | MEN1 (0.40) | MEN1KMT2ATP53POLBPABPC1 | |
| SCHEMBL1624649 | 0.82 | MEN1 (0.43) | MEN1KMT2ATP53POLBPABPC1 | |
| SCHEMBL27600254 | 0.78 | NTRK1 (0.47) | MEN1KMT2ATP53POLBPDE10A | |
| SCHEMBL27600149 | 0.76 | GSR (0.40) | TP53PDE10ASMN1; SMN2MAPT | |
| SCHEMBL27582833 | 0.76 | PDE10A (0.39) | KMT2ATP53PDE10AESR1ESR2 | |
| SCHEMBL27582767 | 0.76 | PDE10A (0.39) | TP53PDE10APDPK1ESR1ESR2 | |
| SCHEMBL27582863 | 0.76 | BMI1 (0.39) | POLBPDE10APDPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101967146-B | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents | RAQUALIA PHARMA INC | 2015-04-08 | — | — | CN | disclosed |