SCHEMBL28008407

SCHEMBL28008407

CCCCCCCCCCCCCCCCCC(=O)Oc1cccc(N)c1N

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.58
POLK Q9UBT6 2/20 0.58
POLL Q9UGP5 2/20 0.58
POLH Q9Y253 2/20 0.58
KDM4E B2RXH2 2/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
RECQL P46063 1/20 0.52
ALOX15 P16050 1/20 0.48
PPARG P37231 2/20 0.45
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TOP2A P11388 2/20 0.44
PPARA Q07869 1/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3664381 0.89 KDM4E (0.57) POLMPOLKPOLLPOLHKDM4E
SCHEMBL3664563 0.89 KDM4E (0.57) POLMPOLKPOLLPOLHKDM4E
SCHEMBL5271391 0.89 KDM4E (0.57) POLMPOLKPOLLPOLHKDM4E
SCHEMBL27834615 0.88 KDM4E (0.59) POLMPOLKPOLLPOLHKDM4E
SCHEMBL30262708 0.88 KDM4E (0.59) POLMPOLKPOLLPOLHKDM4E
SCHEMBL28834444 0.87 KDM4E (0.46) POLMPOLKPOLLPOLHKDM4E
SCHEMBL7320538 0.85 POLM (0.54) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15546549 0.84 KMT2A (0.66) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15549473 0.84 KMT2A (0.66) POLMPOLKPOLLPOLHKDM4E
SCHEMBL15549264 0.84 KMT2A (0.66) POLMPOLKPOLLPOLHKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104656311-A Manufacturing method for liquid crystal alignment film, substrate for liquid crystal display device and manufacturing method thereof, and liquid crystal display device JSR CORP 2015-05-27 CN disclosed