Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.54 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.54 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.54 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389447 | 0.95 | MEN1 (0.57) | POLMPOLKPOLLPOLHMEN1 | |
| Hydrochloric Acid SCHEMBL27537273 | 0.94 | MEN1 (0.56) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL6667343 | 0.89 | MEN1 (0.45) | POLMPOLKPOLLPOLHMEN1 | |
| Hydrochloric Acid SCHEMBL8951311 | 0.88 | MEN1 (0.44) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL28309018 | 0.86 | POLM (0.59) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL9179143 | 0.86 | POLM (0.59) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL11577818 | 0.86 | POLM (0.59) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL2293567 | 0.86 | MEN1 (0.60) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL28008407 | 0.85 | POLM (0.58) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL7038030 | 0.84 | KMT2A (0.41) | POLMPOLKPOLLPOLHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |