Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.39 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.39 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.39 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439301 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1AHRRAB9A | |
| SCHEMBL620331 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL30891041 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL3567491 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL3366468 | 0.77 | MAPT (0.50) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL28110425 | 0.77 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1AHRRAB9A | |
| SCHEMBL516896 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29659762 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL31378791 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1AHRRAB9A | |
| SCHEMBL18743108 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447740-B | Imidazolone derivative as well as drug composition and application thereof | 北京富龙康泰生物技术有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104411706-A | Imidazolone derivatives, pharmaceutical compositions and uses thereof | BEIJING FORELANDPHARMA CO LTD | 2015-03-11 | — | — | CN | disclosed |