SCHEMBL28008484

SCHEMBL28008484

CCCCC(C(=O)O)(C(=O)O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.52
NR5A1 Q13285 1/20 0.52
CYP1A2 P05177 3/20 0.43
CYP3A4 P08684 3/20 0.43
TSHR P16473 3/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
LMNA P02545 2/20 0.41
RECQL P46063 1/20 0.41
GABBR2 O75899 2/20 0.40
GABBR1 Q9UBS5 2/20 0.40
GLRA3 O75311 1/20 0.40
GLRB P48167 1/20 0.40
KMT2A Q03164 3/20 0.39
GAA P10253 2/20 0.39
GPR55 Q9Y2T6 1/20 0.39
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 2/20 0.39
MAPK1 P28482 2/20 0.39
BLM P54132 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27860427 0.91 NR5A2 (0.48) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL4613191 0.80 NR5A2 (0.50) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL28251515 0.79 NR5A2 (0.49) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL1719554 0.78 NR5A2 (0.48) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL27507495 0.78 NR5A2 (0.57) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL27372566 0.77 NR5A2 (0.47) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL462662 0.77 ALDH1A1 (0.49) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL28952443 0.77 NR5A2 (0.46) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL5415844 0.77 NR5A2 (0.46) NR5A2NR5A1CYP1A2CYP3A4TSHR
SCHEMBL11782328 0.77 NR5A2 (0.46) NR5A2NR5A1CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108211519-A A kind of flame-proof antibiotic air filtration material and preparation method thereof 江苏尚科聚合新材料有限公司 2018-06-29 CN disclosed
CN-104540895-A Aliphatic polyester resin composition and biodegradable film MITSUBISHI PLASTICS AGRI DREAM CO LTD 2015-04-22 CN disclosed