Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209986 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4EPGK1HTT | |
| SCHEMBL16689300 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1KDM4EPGK1HTT | |
| SCHEMBL14367995 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1KDM4EPGK1HTT | |
| SCHEMBL6767043 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1KDM4EPGK1HTT | |
| SCHEMBL16689327 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1KDM4EPGK1HTT | |
| SCHEMBL7652710 | 0.78 | SLC10A2 (0.40) | SMN1; SMN2ALDH1A1KDM4EPGK1HTT | |
| SCHEMBL6764873 | 0.76 | TNF (0.44) | SMN1; SMN2ALDH1A1KDM4EHTTEGFR | |
| SCHEMBL6767322 | 0.76 | SLC10A2 (0.46) | SMN1; SMN2ALDH1A1KDM4ETUBB4ATUBB | |
| SCHEMBL16689304 | 0.75 | HSP90AA1 (0.39) | SMN1; SMN2ALDH1A1KDM4EHTTCA1 | |
| SCHEMBL6951164 | 0.74 | PDGFRB (0.41) | SMN1; SMN2ALDH1A1KDM4EKDRSLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662015-A | Complement pathway modulators and uses thereof | NOVARTIS AG | 2015-05-27 | — | — | CN | disclosed |