SCHEMBL28008804

SCHEMBL28008804

CC(C)CC(=O)CC(=O)C(C)(C)C.[Zn]

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.42
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA2 P00918 1/20 0.36
ACHE P22303 1/20 0.33
PTPN1 P18031 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1262761 0.98 CYP2C19 (0.43) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL20420607 0.86 CYP2C19 (0.36) CYP2C19ALDH1A1TDP1CA2
SCHEMBL11974569 0.80 CYP2C19 (0.41) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL23009498 0.80 CYP2C19 (0.41) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL2126093 0.78 CYP2C19 (0.39) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL269050 0.78 ALDH1A1 (0.48) CYP2C19ALDH1A1TDP1CA2PTPN1
SCHEMBL1435016 0.77 CYP2C19 (0.42) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL1924519 0.77 ALDH1A1 (0.53) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL11003812 0.77 KMT2A (0.36) ALDH1A1TDP1
SCHEMBL6135386 0.77 CYP2C19 (0.38) CYP2C19ALDH1A1TDP1CA2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102223953-B Novel catalysts for the reaction between an isocyanate and an alcohol BLUESTAR SILICONES FRANCE 2015-05-20 CN disclosed