SCHEMBL28008951

SCHEMBL28008951

O=c1c2ccccc2nc(-c2ccccc2)n1Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
LMNA P02545 3/20 1.00
RAB9A P51151 2/20 1.00
RECQL P46063 1/20 1.00
KMT2A Q03164 2/20 0.84
MEN1 O00255 1/20 0.84
CYP1A2 P05177 2/20 0.82
CYP2C9 P11712 2/20 0.82
CYP2C19 P33261 2/20 0.82
GAA P10253 1/20 0.82
CYP2D6 P10635 1/20 0.82
CASR P41180 2/20 0.74
TSHR P16473 3/20 0.67
PKM P14618 1/20 0.67
PDE6D O43924 1/20 0.65
ALDH2 P05091 1/20 0.65
ALDH3A1 P30838 1/20 0.65
POLB P06746 1/20 0.61
F11 P03951 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10609253 0.87 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL6309810 0.87 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL5777984 0.85 CASR (1.00) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL6306194 0.85 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL11012826 0.83 CASR (0.72) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL30227085 0.83 CASR (0.72) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL28738320 0.81 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL12354226 0.81 CASR (0.77) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL6309602 0.81 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2LMNARAB9ARECQL
SCHEMBL11008746 0.80 CASR (0.72) ALDH1A1SMN1; SMN2LMNARAB9ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241447-A Method for synthesizing quinazolinone and derivative thereof through photocatalysis three-component serial reaction 淮阴工学院 2025-01-03 CN disclosed
CN-104496915-A Synthetic method of quinazolinone aromatic compound UNIV HUAQIAO 2015-04-08 CN disclosed