SCHEMBL28009088

SCHEMBL28009088

C=C(C)C(=O)OCCC#N.N#CCCCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.44
THRB P10828 1/20 0.41
TDP1 Q9NUW8 3/20 0.38
POLB P06746 2/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
ALDH1A1 P00352 5/20 0.33
PTPN7 P35236 5/20 0.33
RECQL P46063 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
MCL1 Q07820 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HMGCR P04035 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28008586 0.95 TSHR (0.42) TSHRTHRBTDP1POLBAPEX1
SCHEMBL28008580 0.91 MAPT (0.44) TSHRTHRBTDP1POLBAPEX1
Valeric Acid SCHEMBL28818284 0.91 TSHR (0.53) TSHRTHRBTDP1ALDH1A1PTPN7
SCHEMBL28008638 0.90 THRB (0.43) TSHRTHRBTDP1POLBAPEX1
Hexanoate SCHEMBL28008581 0.90 TSHR (0.55) TSHRTDP1ALDH1A1PTPN7MEN1
Butyric Acid SCHEMBL28009061 0.88 TSHR (0.47) TSHRTHRBTDP1POLBAPEX1
SCHEMBL28008563 0.87 MAPT (0.50) TSHRTHRBTDP1POLBAPEX1
Acetic Acid SCHEMBL28158415 0.87 THRB (0.48) TSHRTHRBTDP1POLBAPEX1
SCHEMBL33780 0.87 THRB (0.52) TSHRTHRBTDP1POLBAPEX1
Propionic Acid SCHEMBL28009092 0.85 THRB (0.49) TSHRTHRBTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104795595-A Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES 2015-07-22 CN claimed
CN-104795595-A Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES 2015-07-22 CN disclosed
CN-102498605-B Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES 2015-05-20 CN disclosed