Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27952651 | 0.92 | STAT3 (0.34) | STAT3STAT1NPC1MAPTRAB9A | |
| SCHEMBL27654353 | 0.89 | STAT3 (0.34) | STAT3STAT1NPC1MAPTRAB9A | |
| SCHEMBL27554464 | 0.86 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL28002967 | 0.85 | MAPT (0.46) | NPC1MAPTRAB9AMMP2MMP9 | |
| SCHEMBL29430977 | 0.83 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL30821407 | 0.83 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL9404765 | 0.81 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL9718830 | 0.81 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL1629005 | 0.81 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL23456860 | 0.81 | STAT3 (0.41) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650103-B | A kind of pyrene tetrone bridging molecules pincers series metal porphyrin compound and preparation method | 北京理工大学 | 2016-08-24 | — | — | CN | claimed |
| CN-105254639-A | Serial compounds with triptycene as framework and in bridge connection with metalloporphyrin through pyrene tetrone and preparation method therefor | BEIJING INST TECHNOLOGY | 2016-01-20 | — | — | CN | claimed |
| CN-104650103-A | Pyrene tetrone bridging molecular tweezers-series metalloporphyrin compound and preparation method thereof | BEIJING INST TECHNOLOGY | 2015-05-27 | — | — | CN | claimed |
| CN-104650103-B | A kind of pyrene tetrone bridging molecules pincers series metal porphyrin compound and preparation method | 北京理工大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-105254639-A | Serial compounds with triptycene as framework and in bridge connection with metalloporphyrin through pyrene tetrone and preparation method therefor | BEIJING INST TECHNOLOGY | 2016-01-20 | — | — | CN | disclosed |
| CN-105254639-A | Serial compounds with triptycene as framework and in bridge connection with metalloporphyrin through pyrene tetrone and preparation method therefor | BEIJING INST TECHNOLOGY | 2016-01-20 | — | — | CN | disclosed |
| CN-104650103-A | Pyrene tetrone bridging molecular tweezers-series metalloporphyrin compound and preparation method thereof | BEIJING INST TECHNOLOGY | 2015-05-27 | — | — | CN | disclosed |