SCHEMBL30821407

SCHEMBL30821407

C1=Cc2cc3ccc(cc4nc(cc5ccc(cc1n2)[nH]5)C=C4)[nH]3

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.42
▸ STAT1 P42224 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15809 1.00 STAT3 (0.42) STAT3STAT1
SCHEMBL9430673 1.00 STAT3 (0.42) STAT3STAT1
SCHEMBL29430977 1.00 STAT3 (0.42) STAT3STAT1
SCHEMBL6517023 1.00 STAT3 (0.42) STAT3STAT1
SCHEMBL6744970 1.00 STAT3 (0.42) STAT3STAT1
SCHEMBL9717057 0.97 STAT3 (0.41) STAT3STAT1
SCHEMBL21729 0.97 STAT3 (0.41) STAT3STAT1
SCHEMBL1603039 0.97 STAT3 (0.41) STAT3STAT1
SCHEMBL705768 0.97 STAT3 (0.41) STAT3STAT1
SCHEMBL1572838 0.97 STAT3 (0.41) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4577250-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2025-07-02 — — EP disclosed
US-12344675-B2 Polypeptide comprising a single-domain antibody variable region that binds delta-like ligand 3 (DLL3) and method of use thereof to make a radionuclide complex Abdera Therapeutics Inc. (US) 2025-07-01 — — US disclosed
US-20250051476-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. 2025-02-13 — — US disclosed
US-20240207462-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (CA) 2024-06-27 — — US disclosed
WO-2024044551-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051476-A1 DLL3 BINDING MOLECULES AND USES THEREOF DLK1, DBNL, DVL3 STAT3 3056/4885STAT1 2497/4885
US-12344675-B2 Polypeptide comprising a single-domain antibody variable region that binds delta-like ligand 3 (DLL3) and method of use thereof to make a radionuclide complex DLK1, CD2BP2, IGLV6-57 STAT3 3120/4885STAT1 2759/4885
US-20240207462-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY FCGR2A, FCGR3B, CD74 STAT3 3389/4885STAT1 3333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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