SCHEMBL28009342

SCHEMBL28009342

FC(F)(F)n1cccc1-c1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA3 P34903 1/20 0.46
KDM4E B2RXH2 7/20 0.45
LMNA P02545 4/20 0.45
CCR1 P32246 2/20 0.45
CCR5 P51681 2/20 0.45
CCR8 P51685 2/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
METAP1 P53582 1/20 0.45
BLM P54132 1/20 0.45
HIF1A Q16665 1/20 0.45
DOHH Q9BU89 1/20 0.45
P4HTM Q9NXG6 1/20 0.45
NPC1 O15118 6/20 0.42
TP53 P04637 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8649665 0.79 NPC1 (0.46) GABRA1GABRG2GABRB3GABRA3KDM4E
Hydrochloric Acid SCHEMBL3807552 0.76 BRD4 (0.43) GABRA1GABRG2GABRB3GABRA3KDM4E
SCHEMBL5163455 0.72 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21677387 0.70 ALDH1A1 (0.38) GABRA1GABRG2GABRB3GABRA3KDM4E
Dipyridyl SCHEMBL8655605 0.68 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL6885910 0.68 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.66 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.66 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.66 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL5922 0.66 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105392771-A Triphenylamine derivative and use therefor NISSAN CHEMICAL IND LTD 2016-03-09 CN disclosed
CN-105324360-A Aniline derivative, charge-transporting varnish, and organic electroluminescent element NISSAN CHEMICAL IND LTD 2016-02-10 CN disclosed
CN-105324370-A Thiophene derivative, use thereof, and production method of thiophene derivative NISSAN CHEMICAL IND LTD 2016-02-10 CN disclosed
CN-104629591-A Charge-transporting varnish, charge-transporting thin film, and organic electroluminescent device NISSAN CHEMICAL IND LTD 2015-05-20 CN disclosed
CN-104513513-A Charge transfer varnish, charge transfer thin film and organic electroluminescence component NISSAN CHEMICAL IND LTD 2015-04-15 CN disclosed
CN-104513512-A Charge transfer varnish, charge transfer thin film and organic electroluminescence component NISSAN CHEMICAL IND LTD 2015-04-15 CN disclosed