Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520483 | 0.89 | LPAR3 (0.40) | LPAR3LPAR1CYP3A4LPAR2SMPD1 | |
| SCHEMBL18423586 | 0.88 | LMNA (0.38) | LPAR3LPAR1CYP3A4LPAR2SMPD1 | |
| SCHEMBL11591189 | 0.83 | LMNA (0.44) | TSHR | |
| SCHEMBL2523264 | 0.82 | LPAR3 (0.50) | LPAR3LPAR1LPAR2SMPD1LPAR5 | |
| SCHEMBL2521045 | 0.82 | LPAR3 (0.50) | LPAR3LPAR1LPAR2SMPD1LPAR5 | |
| SCHEMBL887887 | 0.82 | SMPD1 (0.48) | LPAR3LPAR1CYP3A4LPAR2SMPD1 | |
| Hydrochloric Acid SCHEMBL26928575 | 0.80 | SMPD1 (0.47) | LPAR3LPAR1CYP3A4LPAR2SMPD1 | |
| SCHEMBL22974808 | 0.78 | LPAR3 (0.50) | LPAR3LPAR1LPAR2SMPD1LPAR5 | |
| SCHEMBL37267 | 0.77 | CYP3A4 (0.48) | LPAR3LPAR1CYP3A4TSHR | |
| SCHEMBL2522276 | 0.77 | METAP1 (0.36) | LPAR3LPAR1LPAR2SMPD1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100201939-A1 | PLASTIC LENS AND METHOD OF MANUFACTURING THE SAME | HOYA CORPORATION (JP) | 2010-08-12 | — | — | US | disclosed |
| EP-2172792-A1 | PLASTIC LENS AND METHOD OF MANUFACTURING THE SAME | Hoya Corporation (JP) | 2010-04-07 | — | — | EP | disclosed |