Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289234 | 0.98 | NCEH1 (0.57) | NCEH1KMT2AMEN1SLC6A4MAPT | |
| SCHEMBL27329722 | 0.94 | NCEH1 (0.62) | NCEH1KMT2AMEN1SLC6A4MAPT | |
| SCHEMBL8052307 | 0.90 | NCEH1 (0.58) | NCEH1KMT2AMEN1MAPTCNR1 | |
| SCHEMBL7189144 | 0.89 | NCEH1 (0.59) | NCEH1KMT2AMEN1SLC6A4MAPT | |
| SCHEMBL28387488 | 0.87 | NCEH1 (0.60) | NCEH1KMT2AMEN1SLC6A4MAPT | |
| SCHEMBL29743344 | 0.86 | SLC6A4 (0.51) | NCEH1KMT2AMEN1SLC6A4MAPT | |
| SCHEMBL10999687 | 0.84 | SLC6A4 (0.62) | NCEH1KMT2AMEN1SLC6A4MAPT | |
| SCHEMBL18245166 | 0.81 | SLC6A4 (0.49) | NCEH1KMT2AMEN1SLC6A4MAPT | |
| SCHEMBL18470242 | 0.80 | NCEH1 (0.49) | NCEH1KMT2AMEN1CNR1CNR2 | |
| SCHEMBL2125169 | 0.80 | CYP1A2 (0.47) | NCEH1KMT2AMEN1MAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650110-B | Novel heterocyclic compound, method for producing intermediate therefor, and use thereof | 日本化药株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-103391942-B | Novel heterocyclic compound, method for producing intermediate thereof, and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-104650110-A | Novel heterocyclic compound, method for producing intermediate therefor, and use thereof | NIPPON KAYAKU KK | 2015-05-27 | — | — | CN | disclosed |