SCHEMBL8052307

SCHEMBL8052307

CCCCCCCCc1c(Oc2ccc3ccccc3c2CCCCCCCC)ccc2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 3/20 0.58
GAA P10253 4/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
TLR8 Q9NR97 2/20 0.43
MAPT P10636 1/20 0.43
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HTT P42858 3/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7189144 0.98 NCEH1 (0.59) NCEH1GAATDP1L3MBTL1CNR1
SCHEMBL28010488 0.90 NCEH1 (0.56) NCEH1CNR1CNR2MAPTMEN1
SCHEMBL9289234 0.89 NCEH1 (0.57) NCEH1CNR1CNR2MAPTMEN1
SCHEMBL7694803 0.83 NCEH1 (0.45) NCEH1TDP1MAPTALDH1A1KMT2A
SCHEMBL27329722 0.83 NCEH1 (0.62) NCEH1GAATDP1L3MBTL1MAPT
SCHEMBL18470242 0.83 NCEH1 (0.49) NCEH1GAATDP1L3MBTL1CNR1
SCHEMBL2125169 0.83 CYP1A2 (0.47) NCEH1GAACNR1TLR8MAPT
SCHEMBL8671922 0.83 CYP1A2 (0.47) NCEH1GAACNR1TLR8MAPT
SCHEMBL2127033 0.83 CYP1A2 (0.47) NCEH1GAACNR1TLR8MAPT
SCHEMBL11381159 0.81 TYR (0.47) NCEH1GAATDP1TLR8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0285608-B2 WATER-IN-OIL EMULSIONS LUBRIZOL CORP (US) 2000-05-17 EP disclosed
EP-0333754-B1 EXPLOSIVE COMPOSITIONS LUBRIZOL CORP (US) 1995-07-26 EP disclosed
EP-0285608-B1 WATER-IN-OIL EMULSIONS The Lubrizol Corporation (US) 1990-08-01 EP disclosed
EP-0364511-A1 WATER-IN-OIL EMULSIONS The Lubrizol Corporation (US) 1990-04-25 EP disclosed
EP-0116399-B1 DITHIOPHOSPHORUS/AMINE SALTS AND AQUEOUS COMPOSITIONS CONTAINING SAME The Lubrizol Corporation (US) 1990-03-14 EP disclosed
EP-0333754-A1 EXPLOSIVE COMPOSITIONS. LUBRIZOL CORP (US) 1989-09-27 EP disclosed
US-4846985-A HYDROXYSULFIDE OR SECONDARY AMINE COMPOUND THE LUBRIZOL CORPORATION (US) 1989-07-11 US disclosed
US-4844756-A SALT DERIVED FROM HYDROCARBYL-SUBSTITUTED CARBOXYLIC ACID OR ANHYDRIDE OR DERIVATIVE, AND AMMONIA, AN AMINE, OR ALKALI OR ALKALINE EARTH METAL THE LUBRIZOL CORPORATION (US) 1989-07-04 US disclosed
WO-1989005848-A1 WATER-IN-OIL EMULSIONS THE LUBRIZOL CORPORATION (US) 1989-06-29 WO disclosed
US-4840687-A OXIDIZER, REACTION PRODUCT OF A CARBOXYLIC ACLATING AGENT, A POLYAMINE AND AN ACID OR ACID-PRODUCING COMPOUND THE LUBRIZOL CORPORATION (US) 1989-06-20 US disclosed
EP-0285608-A1 WATER-IN-OIL EMULSIONS. LUBRIZOL CORP (US) 1988-10-12 EP disclosed
US-4774351-A EXTREME PRESSURE LUBRICANTS, WEAR RESISTANCE THE LUBRIZOL CORPORATION (US) 1988-09-27 US disclosed
WO-1988003522-A1 EXPLOSIVE COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1988-05-19 WO disclosed
US-4721802-A EXTREME PRESSURE LUBRICANTS THE LUBRIZOL CORPORATION (US) 1988-01-26 US disclosed
US-4708753-A NITROGEN CONTAINING SALT EMULSIFIERS; HYDRAULIC FLUIDS, EXPLOSIVES, ACIDIZING FLUIDS THE LUBRIZOL CORPORATION (US) 1987-11-24 US disclosed
WO-1987003613-A2 WATER-IN-OIL EMULSIONS THE LUBRIZOL CORPORATION (US) 1987-06-18 WO disclosed
EP-0116399-A2 Dithiophosphorus/amine salts and aqueous compositions containing same The Lubrizol Corporation (US) 1984-08-22 EP disclosed