SCHEMBL28010705

SCHEMBL28010705

CCOC(=O)C(Br)C(Br)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.64
ALDH1A1 P00352 9/20 0.58
L3MBTL1 Q9Y468 1/20 0.49
TSHR P16473 1/20 0.47
GAA P10253 2/20 0.46
KDM4E B2RXH2 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 1/20 0.42
LMNA P02545 1/20 0.42
CES2 O00748 1/20 0.41
ACHE P22303 1/20 0.41
CES1 P23141 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CACNA1D Q01668 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27987013 0.84 ALDH1A1 (0.63) CYP1A2ALDH1A1L3MBTL1TSHRGAA
SCHEMBL10091749 0.84 ALDH1A1 (0.77) CYP1A2ALDH1A1L3MBTL1TSHRGAA
SCHEMBL31198088 0.82 CYP1A2 (0.43) CYP1A2ALDH1A1L3MBTL1GAAKDM4E
SCHEMBL31198114 0.82 CYP1A2 (0.43) CYP1A2ALDH1A1L3MBTL1GAAKDM4E
SCHEMBL31198065 0.81 MAPT (0.47) CYP1A2ALDH1A1L3MBTL1KDM4ERAB9A
SCHEMBL31198057 0.81 MAPT (0.47) CYP1A2ALDH1A1L3MBTL1KDM4ERAB9A
SCHEMBL31198103 0.81 MEN1 (0.45) CYP1A2ALDH1A1L3MBTL1TSHRSMN1; SMN2
SCHEMBL31198113 0.81 MEN1 (0.45) CYP1A2ALDH1A1L3MBTL1TSHRSMN1; SMN2
SCHEMBL15515514 0.80 ALDH1A1 (0.58) CYP1A2ALDH1A1L3MBTL1TSHRGAA
SCHEMBL8702322 0.79 ALDH1A1 (0.57) CYP1A2ALDH1A1L3MBTL1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118930434-A 2, 3-Dibromopropionate compound, and preparation method and application thereof 陕西省生物农业研究所 2024-11-12 CN disclosed
CN-104529925-A 5-(4-nitrophenyl)-3-hydroxylisoxazole and preparation process and use thereof WUHAN INST TECHNOLOGY 2015-04-22 CN disclosed