SCHEMBL28010708

SCHEMBL28010708

CC[C@H](CC(=O)c1ccccc1)c1ccc(C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
ATM Q13315 1/20 0.55
NPC1 O15118 4/20 0.54
KMT2A Q03164 4/20 0.54
RAB9A P51151 3/20 0.54
MEN1 O00255 2/20 0.54
MGAM O43451 2/20 0.51
GAA P10253 2/20 0.51
SI P14410 2/20 0.51
MGAM2 Q2M2H8 2/20 0.51
ALDH1A1 P00352 3/20 0.49
LMNA P02545 3/20 0.49
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
POLB P06746 2/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TSHR P16473 1/20 0.47
PTPN1 P18031 2/20 0.47
RECQL P46063 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2579321 1.00 L3MBTL1 (0.59) L3MBTL1ATMNPC1KMT2ARAB9A
SCHEMBL12158725 1.00 L3MBTL1 (0.59) L3MBTL1ATMNPC1KMT2ARAB9A
SCHEMBL2581702 0.90 ATM (0.66) L3MBTL1ATMNPC1KMT2AMEN1
SCHEMBL28114650 0.90 ATM (0.66) L3MBTL1ATMNPC1KMT2AMEN1
SCHEMBL12158645 0.90 ATM (0.66) L3MBTL1ATMNPC1KMT2AMEN1
SCHEMBL12158733 0.86 L3MBTL1 (0.57) L3MBTL1ATMNPC1KMT2ARAB9A
SCHEMBL2587322 0.86 L3MBTL1 (0.57) L3MBTL1ATMNPC1KMT2AMEN1
SCHEMBL12158730 0.86 L3MBTL1 (0.57) L3MBTL1ATMNPC1KMT2AMEN1
SCHEMBL12158732 0.86 L3MBTL1 (0.57) L3MBTL1ATMNPC1KMT2AMEN1
SCHEMBL28837037 0.86 L3MBTL1 (0.57) L3MBTL1ATMNPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104530122-B Dinaphthol phosphoramidite ligand, its synthetic method and the application thereof of dendrimer, dendritic polymer load 商丘师范学院 2016-11-30 CN disclosed
CN-104530122-A Dendrimer polymer loaded binaphthol phosphoramidite ligand as well as synthesis method and application thereof UNIV SHANGQIU NORMAL 2015-04-22 CN disclosed