Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28010853 | 0.78 | PRKDC (0.47) | MEN1KMT2AMTORPRKDCPOLB | |
| SCHEMBL23147723 | 0.71 | MEN1 (0.36) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28331999 | 0.69 | PLA2G10 (0.48) | ALDH1A1MEN1KMT2APLA2G10OPRM1 | |
| SCHEMBL29715262 | 0.68 | AURKA (0.41) | GAAALDH1A1MAPTPIK3CAMTOR | |
| SCHEMBL11328980 | 0.67 | MEN1 (0.46) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27667941 | 0.65 | GAA (0.50) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30995195 | 0.65 | NOTUM (0.42) | GAAALDH1A1MEN1KMT2APIK3CA | |
| SCHEMBL29812968 | 0.64 | TYK2 (0.31) | — | |
| SCHEMBL27318192 | 0.63 | NOTUM (0.46) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29715223 | 0.62 | AURKA (0.38) | GAAALDH1A1MEN1KMT2APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603106-B | Indole carboxamide derivatives and uses thereof | 诺华股份有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-104603106-A | Indole carboxamide derivatives and uses thereof | NOVARTIS AG | 2015-05-06 | — | — | CN | disclosed |