SCHEMBL2801141

SCHEMBL2801141

C=CC=CC1CCCCC(=O)N1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2687621 0.81 CRBN (0.33) CA1CA2CA4KMT2A
SCHEMBL28426745 0.79 KMT2A (0.33) CA1CA2CA4KMT2A
SCHEMBL3071586 0.75 CRBN (0.34) CA1CA2CA4KMT2A
SCHEMBL9666729 0.75
SCHEMBL2421448 0.74 HTT (0.33)
SCHEMBL10714938 0.74
SCHEMBL11199281 0.74 BACE1 (0.33)
SCHEMBL2053316 0.74
SCHEMBL6977541 0.74 BACE1 (0.33) CA1CA2CA4
SCHEMBL7433757 0.73 KMT2A (0.34) CA1CA2CA4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100215948-A1 RUBBERY-BLOCK CONTAINING POLYMERS, FIBER SIZINGS THEREOF AND COMPOSITES THEREOF UNIVERSITY OF DELAWARE (US) 2010-08-26 US disclosed
WO-2010096543-A2 RUBBERY-BLOCK CONTAINING POLYMERS, FIBER SIZINGS THEREOF AND COMPOSITES THEREOF UNIVERSITY OF DELAWARE (US) 2010-08-26 WO disclosed
EP-0103148-B1 IMPACT RESISTANT POLYMERIC COMPOSITIONS CONTAINING POLYAMIDES, MALEIC ANHYDRIDE ADDUCTS OF HYDROGENATED POLYMERS AND GRAFT COPOLYMERS THEREOF THE FIRESTONE TIRE & RUBBER COMPANY (US) 1986-12-30 EP disclosed
US-4427828-A Impact resistant polymeric compositions containing polyamides, maleic anhydride adducts of hydrogenated polymers and graft copolymers thereof THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-01-24 US disclosed
US-4055534-A MOLECULAR WEIGHT, DIISOCYANATE HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1977-10-25 US disclosed