⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687621 | 0.80 | CRBN (0.33) | — | |
| SCHEMBL11199281 | 0.79 | BACE1 (0.33) | — | |
| SCHEMBL28426745 | 0.78 | KMT2A (0.33) | — | |
| SCHEMBL2801141 | 0.74 | CA1 (0.31) | — | |
| SCHEMBL9666729 | 0.74 | — | — | |
| SCHEMBL3071586 | 0.74 | CRBN (0.34) | — | |
| SCHEMBL5197876 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL20445551 | 0.72 | KMT2A (0.34) | — | |
| SCHEMBL7433757 | 0.72 | KMT2A (0.34) | — | |
| SCHEMBL20444035 | 0.72 | KMT2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124274-B1 | ELECTRON BEAM SENSITIVE MIXTURE RESIST | GAF CORPORATION (US) | 1988-06-22 | — | — | EP | claimed |
| US-4375398-A | CROSSLINKING, VINYL ETHER | GAF CORPORATION (US) | 1983-03-01 | — | — | US | claimed |